Applying radiobiology to clinical molecular radiotherapy

Radiobiology and molecular oncology: how are they changing radiotherapy in clinical practice?

Fast-neutron radiobiology and radiotherapy.

The application of fast neutrons, negative pions or heavy ions will only provide an advantage for the radiotherapy of cancer if, in comparison with conventional radiations, e.g., X-rays, gamma rays and electrons, better depth-dose and collimation characteristics or specific radiobiological dose response relationships result in greater local control probabilities for tumours without increased fr...

THE ROLE OF RADIOBIOLOGY Radiotherapy

Melatonin/IonizingRadiation/Radiobiology/RadioprotectiyelRadiotherapy/RepalrEnzyme. In spite of the fact that radiotherapy is a common and effective tool fOr cancer treatment; the radio sensitivity of normal tissues adjacent to the tumor which are unavoidably exposed to radiation limits therapeutic gain. For the sake of improvement in radiation therapy, radiobiologythe study of the action of io...

Skin and other reactions to radiotherapy--clinical presentation and radiobiology of skin reactions.

The skin represented the dose-limiting organ in radiotherapy over long periods of time. In the first third of the 20th century, radiotherapy was associated with deposition of significant radiation doses in the superficial compartments of the skin. Therefore, all major radiobiological principles, such as effects of fractionation on radiation sensitivity or volume/area effects, were initially bas...

Update on clinical radiobiology

Radiation therapy is an important local cytotoxic modality for cancer treatment whose aim is to control the disease while minimising damage to normal tissue. The combination of different treatment modalities offers a more effective cure and reduction in normal tissue toxicity. However, the differences in genetic profiles can cause diverse treatment outcomes. Multidisciplinary research, where te...